Neuronal migration is a fundamental biological process that underlies proper brain development and neuronal circuit formation. In the developing cerebral cortex, distinct neuronal populations, producing excitatory, inhibitory and modulatory neurotransmitters, are generated in different germinative areas and migrate along various routes to reach their final positions within the cortex. Different technical approaches and experimental models have been adopted to study the mechanisms regulating neuronal migration in the cortex. In this review, we will discuss the most common in vitro, ex vivo and in vivo techniques to visualize and study cortical neuronal migration.

In vitro, ex vivo and in vivo techniques to study neuronal migration in the developing cerebral cortex / R. Azzarelli, R. Oleari, A. Lettieri, V. Andre’, A. Cariboni. - In: BRAIN SCIENCES. - ISSN 2076-3425. - 7:5(2017 May).

In vitro, ex vivo and in vivo techniques to study neuronal migration in the developing cerebral cortex

R. Oleari;A. Lettieri;V. Andre’;A. Cariboni
2017

Abstract

Neuronal migration is a fundamental biological process that underlies proper brain development and neuronal circuit formation. In the developing cerebral cortex, distinct neuronal populations, producing excitatory, inhibitory and modulatory neurotransmitters, are generated in different germinative areas and migrate along various routes to reach their final positions within the cortex. Different technical approaches and experimental models have been adopted to study the mechanisms regulating neuronal migration in the cortex. In this review, we will discuss the most common in vitro, ex vivo and in vivo techniques to visualize and study cortical neuronal migration.
cortex; electroporation; migrating neuron; migration assays; neuroscience (all)
Settore BIO/13 - Biologia Applicata
Settore BIO/09 - Fisiologia
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/550045
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