Plants belonging to Melaleuca genus (Myrtaceae family) are native to Oceania, where they have been used for ages by Aborigine people in Australian traditional medicine, mainly because of their broad-spectrum antimicrobial activity. Although, M. linariifolia, M. dissitiflora, and other species of Melaleuca can also be used, the tea tree oil, an essential oil obtained from M. alternifolia shows the longest history of medicinal uses. Tea tree oil contains for the 80-90% several monoterpenes (terpinen-4-ol, α-terpinene, 1,8-cineol, p-cymene, α-terpineol, α-pinene, terpinolene, limonene, and sabinene). Sesquiterpenes and aromatic compounds further compose this oil. The essential oil of Melaleuca spp. has been reported to possess effective antibacterial and antifungal properties in vitro. In particular, data show that 1,8-cineol, terpinen-4-ol and methyl eugenol play the key role in mediating this oil's antimicrobial activity.
Plants of the Melaleuca Genus as Antimicrobial Agents: From Farm to Pharmacy / J. Sharifi-Rad, B. Salehi, E..M. Varoni, F. Sharopov, Z. Yousaf, S..A. Ayatollahi, F. Kobarfard, M. Sharifi-Rad, M..H. Afdjei, M. Sharifi-Rad, M. Iriti. - In: PHYTOTHERAPY RESEARCH. - ISSN 0951-418X. - 31:10(2017 Oct), pp. 1475-1494.
|Titolo:||Plants of the Melaleuca Genus as Antimicrobial Agents: From Farm to Pharmacy|
|Parole Chiave:||Australian traditional medicine; methyl eugenol; Myrtaceae; tea tree oil; terpinen-4-ol, 1,8-cineol; Pharmacology|
|Settore Scientifico Disciplinare:||Settore AGR/12 - Patologia Vegetale|
|Data di pubblicazione:||ott-2017|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1002/ptr.5880|
|Appare nelle tipologie:||01 - Articolo su periodico|