Magnesium (Mg) and calcium (Ca) are essential cations for women'€™s preconception health. It is well known that, in blood, the concentration of ionized form of these two cations is temporally altered during menstrual cycle, suggesting a correlation between sex steroid hormones and serum calcium and magnesium levels. Evidence from literature suggests that in assisted reproductive technology increasing estrogens during ovarian hyperstimulation may also modulate serum magnesium and calcium levels. Therefore, we first examined total serum magnesium and calcium levels during follicular phase in a large population of infertile patients who underwent intrauterine insemination (IUI). The results were compared to a group of fertile women. Successively, we studied the total serum magnesium and calcium concentrations in infertile patients before and after ovarian hyperstimulation for in vitro fertilization (IVF). Results highlight that total serum concentration of magnesium and calcium does not seem altered in infertile women. During stimulation with gonadotropins, the values of the two cations do not change significantly in ovarian-stimulated women. However, we found a downward trend in the total magnesium and calcium levels in relation to the rising estrogens.

Serum magnesium and calcium levels in infertile women during a cycle of reproductive assistance / E. Grossi, S. Castiglioni, C. Moscheni, P. Antonazzo, I. Cetin, V.M. Savasi. - In: MAGNESIUM RESEARCH. - ISSN 0953-1424. - 30:2(2017 Apr), pp. 35-41. [10.1684/mrh.2017.0421]

Serum magnesium and calcium levels in infertile women during a cycle of reproductive assistance

E. Grossi
Primo
;
S. Castiglioni
Secondo
;
C. Moscheni;P. Antonazzo;I. Cetin
Penultimo
;
V.M. Savasi
Ultimo
2017-04

Abstract

Magnesium (Mg) and calcium (Ca) are essential cations for women'€™s preconception health. It is well known that, in blood, the concentration of ionized form of these two cations is temporally altered during menstrual cycle, suggesting a correlation between sex steroid hormones and serum calcium and magnesium levels. Evidence from literature suggests that in assisted reproductive technology increasing estrogens during ovarian hyperstimulation may also modulate serum magnesium and calcium levels. Therefore, we first examined total serum magnesium and calcium levels during follicular phase in a large population of infertile patients who underwent intrauterine insemination (IUI). The results were compared to a group of fertile women. Successively, we studied the total serum magnesium and calcium concentrations in infertile patients before and after ovarian hyperstimulation for in vitro fertilization (IVF). Results highlight that total serum concentration of magnesium and calcium does not seem altered in infertile women. During stimulation with gonadotropins, the values of the two cations do not change significantly in ovarian-stimulated women. However, we found a downward trend in the total magnesium and calcium levels in relation to the rising estrogens.
Estrogen; In vitro fertilization; Infertility; Intrauterine insemination; Total serum calcium level; Total serum magnesium level; Biochemistry; Molecular Biology; Clinical Biochemistry
Settore MED/04 - Patologia Generale
Settore MED/40 - Ginecologia e Ostetricia
Settore BIO/16 - Anatomia Umana
Article (author)
File in questo prodotto:
File Dimensione Formato  
Magnesium research.pdf

accesso riservato

Tipologia: Publisher's version/PDF
Dimensione 114.34 kB
Formato Adobe PDF
114.34 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/534311
Citazioni
  • ???jsp.display-item.citation.pmc??? 4
  • Scopus 8
  • ???jsp.display-item.citation.isi??? 7
social impact