Sarcopenia, the progressive and generalized loss of skeletal muscle mass and strength/function associated with aging, increases the risk of a vast array of adverse health outcomes, including falls, morbidity, loss of independence, disability, and mortality. As such, sarcopenia poses a huge socioeconomic burden in developed countries. The development and implementation of effective interventions against sarcopenia is therefore a public health priority. A preliminary, fundamental step in such a process entails the agreement of researchers, healthcare professionals and policy-makers around a unique operational definition of sarcopenia. This will facilitate the framing of a definite clinical entity to be incorporated in standard practice, the understanding of the underlying pathophysiology, and the identification of biological targets for drug development.
Sarcopenia: an overview on current definitions, diagnosis and treatment / L. Francesco, C. Riccardo, M. Cesari, T. Matteo, M. Anna Maria, O. Elena, S. Giulia, S. Sara, S. Alex N, P. Anna, M. Emanuele. - In: CURRENT PROTEIN & PEPTIDE SCIENCE. - ISSN 1389-2037. - 19:7(2018), pp. 633-638. [10.2174/1389203718666170607113459]
Sarcopenia: an overview on current definitions, diagnosis and treatment
M. Cesari;
2018
Abstract
Sarcopenia, the progressive and generalized loss of skeletal muscle mass and strength/function associated with aging, increases the risk of a vast array of adverse health outcomes, including falls, morbidity, loss of independence, disability, and mortality. As such, sarcopenia poses a huge socioeconomic burden in developed countries. The development and implementation of effective interventions against sarcopenia is therefore a public health priority. A preliminary, fundamental step in such a process entails the agreement of researchers, healthcare professionals and policy-makers around a unique operational definition of sarcopenia. This will facilitate the framing of a definite clinical entity to be incorporated in standard practice, the understanding of the underlying pathophysiology, and the identification of biological targets for drug development.File | Dimensione | Formato | |
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