A tumor reaching the size of 1 cm(3) (approximately 1 g wet weight) is commonly assumed to contain 1 x 10(9) cells. This paper comments on the probable origin of this "magic" number and on some possible reasons why it has remained in use until now. However, mostly in epithelial tumors (85% of all human tumors) a cell number one order of magnitude smaller would be more realistic.
|Titolo:||Does the cell number 10(9) still really fit one gram of tumor tissue?|
DEL MONTE, UGO (Primo)
|Data di pubblicazione:||1-feb-2009|
|Digital Object Identifier (DOI):||10.4161/cc.8.3.7608|
|Appare nelle tipologie:||01 - Articolo su periodico|