Neuropeptides drive a wide diversity of biological actions and mediate multiple regulatory functions involving all organ systems. They modulate intercellular signalling in the central and peripheral nervous systems as well as the cross talk among nervous and endocrine systems. Indeed, neuropeptides can function as peptide hormones regulating physiological homeostasis (e.g., cognition, blood pressure, feeding behaviour, water balance, glucose metabolism, pain, and response to stress), neuroprotection, and immunomodulation. We aim here to describe the recent advances on the role exerted by neuropeptides in the control of autophagy and its molecular mechanisms since increasing evidence indicates that dysregulation of autophagic process is related to different pathological conditions, including neurodegeneration, metabolic disorders, and cancer.
Current Evidence for a Role of Neuropeptides in the Regulation of Autophagy / E. Catalani, C. De Palma, C. Perrotta, D. Cervia. - In: BIOMED RESEARCH INTERNATIONAL. - ISSN 2314-6133. - 2017(2017), pp. 5856071.1-5856071.10.
|Titolo:||Current Evidence for a Role of Neuropeptides in the Regulation of Autophagy|
|Parole Chiave:||Biochemistry, Genetics and Molecular Biology (all); Immunology and Microbiology (all)|
|Settore Scientifico Disciplinare:||Settore BIO/14 - Farmacologia|
Settore BIO/09 - Fisiologia
Settore BIO/13 - Biologia Applicata
|Data di pubblicazione:||2017|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1155/2017/5856071|
|Appare nelle tipologie:||01 - Articolo su periodico|