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IRIS è il sistema di gestione integrata dei dati della ricerca (persone, progetti, pubblicazioni, attività) adottato dall'Università degli Studi di Milano.
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EnglishFunctional analysis of CT imaging in lung-transplanted patients is an emerging tool for the interpretation of parenchymal (patterns) evolution after lung transplantation (LT). Aim of this study was to determine the trends of pulmonary function (PFT) indices and quantitative CT parameters within 1-year followup. We prospectively collected PFT parameters (FEV1, FVC) and inspiration/expiration CT scans of LT patients at standard time-points (3-6-12 months). Specific gas volume (SV , ml/g) was measured on CT images as previously described (Salito et al, Radiology 2009; Aliverti et al, ERJ 2013). Selected quantitative indexes were lung volume at inspiration (V ) and the difference between inspiration and expiration SV normalized on expiration SV : ΔSV /SV EXP. Patients who experienced uneventful 12 months postoperative course after bilateral LT were included. Fifteen patients completed the trial. As expected, FEV1 and FVC values significantly improved at each time-point until the 12-month check. Correspondingly, V and ΔSV / SV EXP increased in the same fashion with a trend toward healthy values (Fig1, bottom panels). This preliminary trial evidenced the reliability of specific gas volume analysis as an attractive quantitative CT parameter of lung function after LT. Future studies are requested to verify the accuracy of specific gas volume analysis in the evaluation of patients with lung allograft dysfunction.
Reliability of computed tomography (CT) quantitative analysis in lung transplantation follow-up / C. Salito, F. Pennati, V. Rossetti, M. Pappalettera, P. Tarsia, M. Carrinola, M. Montoli, P. Biondetti, M. Nosotti, A. Palleschi, A. Aliverti. ((Intervento presentato al 27. convegno ERS International Congress 2017 / European Respiratory Society’s International Congress tenutosi a Milano nel 2017.
| Titolo: | Reliability of computed tomography (CT) quantitative analysis in lung transplantation follow-up |
| Autori: | |
| Data di pubblicazione: | set-2017 |
| Parole Chiave: | Treatments; Imaging; Biomakers |
| Settore Scientifico Disciplinare: | Settore MED/21 - Chirurgia Toracica Settore MED/10 - Malattie dell'Apparato Respiratorio |
| Tipologia: | Conference Object |
| Citazione: | Reliability of computed tomography (CT) quantitative analysis in lung transplantation follow-up / C. Salito, F. Pennati, V. Rossetti, M. Pappalettera, P. Tarsia, M. Carrinola, M. Montoli, P. Biondetti, M. Nosotti, A. Palleschi, A. Aliverti. ((Intervento presentato al 27. convegno ERS International Congress 2017 / European Respiratory Society’s International Congress tenutosi a Milano nel 2017. |
| Appare nelle tipologie: | 14 - Intervento a convegno non pubblicato |
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| ERS 2017 (Reliability of computed tomography...).pdf | Altro | Open Access Visualizza/Apri |
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