Mucoepidermoid carcinoma (MEC) represents 15% of all salivary glands malignancies. Metastatic disease at diagnosis is observed in less than 5% of the cases. The lung is the most commonly involved site. This is the first reported case of high-grade MEC of the salivary gland with skin metastases at diagnosis. This feature was associated with a chemoresistant and aggressive behaviour. Differential diagnosis between metastatic MEC and primary skin MEC is essential for therapeutic management and prognosis.
Primary high-grade mucoepidermoid carcinoma of the minor salivary glands with cutaneous metastases at diagnosis / L.D. Locati, P. Quattrone, N. Pizzi, A. Fior, G. Cantù, L. Licitra. - In: ORAL ONCOLOGY. - ISSN 1368-8375. - 38:4(2002 Jun), pp. 401-404.
Primary high-grade mucoepidermoid carcinoma of the minor salivary glands with cutaneous metastases at diagnosis
L. LicitraUltimo
2002
Abstract
Mucoepidermoid carcinoma (MEC) represents 15% of all salivary glands malignancies. Metastatic disease at diagnosis is observed in less than 5% of the cases. The lung is the most commonly involved site. This is the first reported case of high-grade MEC of the salivary gland with skin metastases at diagnosis. This feature was associated with a chemoresistant and aggressive behaviour. Differential diagnosis between metastatic MEC and primary skin MEC is essential for therapeutic management and prognosis.
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