Fibroblast growth factors (FGFs) comprise several peptides that, by interacting with a family of FGF receptors, participate in brain development and contribute to neuronal repair and plasticity. Recent evidence suggests that the expression of FGFs is altered in mood disorders and can be regulated by psychotropic drugs. This provides further support to the notion that neurotrophic molecules might have a role in the etiology and treatment of mental disorders. (copyright) 2005 Elsevier Ltd. All rights reserved.

Emerging role of the FGF system in psychiatric disorders / M.A. Riva, R. Molteni, F. Bedogni, G.A. Racagni, F. Fumagalli,. - In: TRENDS IN PHARMACOLOGICAL SCIENCES. - ISSN 0165-6147. - 26:5(2005), pp. 228-231.

Emerging role of the FGF system in psychiatric disorders

M.A. Riva
Primo
;
R. Molteni
Secondo
;
G.A. Racagni;F. Fumagalli
Penultimo
2005

Abstract

Fibroblast growth factors (FGFs) comprise several peptides that, by interacting with a family of FGF receptors, participate in brain development and contribute to neuronal repair and plasticity. Recent evidence suggests that the expression of FGFs is altered in mood disorders and can be regulated by psychotropic drugs. This provides further support to the notion that neurotrophic molecules might have a role in the etiology and treatment of mental disorders. (copyright) 2005 Elsevier Ltd. All rights reserved.
brain development ; depression ; human ; mental disease ; mood disorder ; nerve cell plasticity ; nerve cell ; nerve regeneration ; neuropathology ; nonhuman ; priority journal ; protein expression ; protein family ; protein function ; regulatory mechanism ; review ; schizophrenia ; clozapine ; diazepam ; fibroblast growth factor receptor ; fibroblast growth factor ; fluoxetine plus olanzapine ; psychotropic agent ; serotonin uptake inhibitor
Settore BIO/14 - Farmacologia
2005
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/5219
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