In a case-control study of 1031 epithelial ovarian cancers and 2311 controls conducted in Italy, 56 cases and 116 controls reported history of benign ovarian cysts, corresponding to a relative risk of 1.3 (95% confidence interval = 0.9-1.8). In a subset of 255 histologically reviewed cases, mucinous and endometrioid ovarian neoplasms and neoplasms of stage I or II arose more frequently from cysts, while use of oral contraceptives or parity were not significantly related to history of ovarian cysts.
Origin of ovarian cancer from benign cysts / L. Dal Maso, V. Canzonieri, R. Talamini, S. Franceschi, C. La Vecchia. - In: EUROPEAN JOURNAL OF CANCER PREVENTION. - ISSN 0959-8278. - 10:2(2001 Apr), pp. 197-199. [10.1097/00008469-200104000-00016]
Origin of ovarian cancer from benign cysts
C. La Vecchia
2001
Abstract
In a case-control study of 1031 epithelial ovarian cancers and 2311 controls conducted in Italy, 56 cases and 116 controls reported history of benign ovarian cysts, corresponding to a relative risk of 1.3 (95% confidence interval = 0.9-1.8). In a subset of 255 histologically reviewed cases, mucinous and endometrioid ovarian neoplasms and neoplasms of stage I or II arose more frequently from cysts, while use of oral contraceptives or parity were not significantly related to history of ovarian cysts.
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