The physiopathology of fatty liver and metabolic syndrome are influenced by diet, life style and inflammation, which have a major impact on the severity of the clinicopathologic outcome of non-alcoholic fatty liver disease. A short comprehensive review is provided on current knowledge of the pathophysiological interplay among major circulating effectors/mediators of fatty liver, such as circulating lipids, mediators released by adipose, muscle and liver tissues and pancreatic and gut hormones in relation to diet, exercise and inflammation.

Pathophysiology of Non Alcoholic Fatty Liver Disease / S. Petta, A. Gastaldelli, E. Rebelos, E. Bugianesi, P. Messa, L. Miele, G. Svegliati Baroni, L. Valenti, F. Bonino. - In: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. - ISSN 1422-0067. - 17:12(2016 Dec 11). [10.3390/ijms17122082]

Pathophysiology of Non Alcoholic Fatty Liver Disease

P. Messa;L. Valenti
Penultimo
;
2016

Abstract

The physiopathology of fatty liver and metabolic syndrome are influenced by diet, life style and inflammation, which have a major impact on the severity of the clinicopathologic outcome of non-alcoholic fatty liver disease. A short comprehensive review is provided on current knowledge of the pathophysiological interplay among major circulating effectors/mediators of fatty liver, such as circulating lipids, mediators released by adipose, muscle and liver tissues and pancreatic and gut hormones in relation to diet, exercise and inflammation.
adiponectin; cholesterol; fatty liver; free fatty acids; ghrelin; glucagon; glucagon-like peptide 1; insulin; insulin resistance; irisin; leptin; selenoprotein P; adipose tissue; gastrointestinal hormones; humans; lipids; muscles; non-alcoholic fatty liver disease; pancreatic hormones
Settore MED/14 - Nefrologia
11-dic-2016
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/516650
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