Comparing techniques to achieve high accuracy and low cost : how should we first diagnose Crohn's disease?

CD is a life-llong inflammatory disease with a world-wide increasing incidence. It is frequently characterized by nonspecific symptoms which need to be differentiated from several intestinal disorders. Despite diagnostic advancements, CD diagnosis remains difficult and frequently challenging. Factors contributing to CD diagnosis delay may include improper use of diagnostic tools. Recent evidence suggests that a selection and a proper sequential use of noninvasive and low-cost diagnostic tests in specific clinical contexts may contribute to direct, speed up and increase the rate of CD diagnosis besides, more importantly, avoiding unnecessary costly investigations.