Cyclopentadienone-based iron complexes were used for the first time to successfully catalyze the diastereoselective hydrogenation of enantiopure imines. Chiral amines, including valuable biologically active products, were obtained often as enantiomerically pure compounds. Computational studies helped to elucidate the chemical and stereochemical aspects of the iron-catalyzed reaction.

Iron catalyzed diastereoselective hydrogenation of chiral imines / D. Brenna, S. Rossi, F. Cozzi, M. Benaglia. - In: ORGANIC & BIOMOLECULAR CHEMISTRY. - ISSN 1477-0539. - 15:27(2017 Jul 21), pp. 5685-5688. [10.1039/c7ob01123g]

Iron catalyzed diastereoselective hydrogenation of chiral imines

D. Brenna
Primo
;
S. Rossi
Secondo
;
F. Cozzi
Penultimo
;
M. Benaglia
Ultimo
2017

Abstract

Cyclopentadienone-based iron complexes were used for the first time to successfully catalyze the diastereoselective hydrogenation of enantiopure imines. Chiral amines, including valuable biologically active products, were obtained often as enantiomerically pure compounds. Computational studies helped to elucidate the chemical and stereochemical aspects of the iron-catalyzed reaction.
Settore CHIM/06 - Chimica Organica
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/513172
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