Incidence of use of various myocardial infarct treatments in 2 Swiss regions

Two regions in Switzerland (Vaud-Fribourg and Ticino) participate in the WHO MONICA project (MONItoring of trends and determinants in CArdiovascular disease). Within this context, all hospitalizations of men for ischemic heart disease will be recorded during a period of ten years. All cases are classified according to uniform criteria, in three categories: definite myocardial infarction, possible myocardial infarction or no myocardial infarction. In 1986, the records were completed with a summary of treatments. The treatment of 334 patients with definite myocardial infarction, aged between 25 and 64 years, surviving after 27 days are analyzed (VD-FR: 217; TI: 117). Results show that anticoagulants were administered in a routine fashion (in 97% of the cases), whilst thrombolysis, applied in 1986 by only one hospital in each area, concerned only 9% of the patients. As compared to Ticino, VD-FR distinguished itself by its significantly higher use of anti-arrhythmia drugs (69% versus 47%; p less than 0.005), nitrates (97% versus 86%; p less than 0.005) and beta-blockers (57% versus 43%; p less than 0.05). Furthermore, patients from VD-FR spent more time in the intensive care unit (6.4 versus 3.7 days; p less than 0.005) and participated more frequently in rehabilitation programmes (47% versus 12%; p less than 0.005). The discussion compares the observed therapy with results published in the literature.