At enrolment (T0) three on combination antiretroviral therapy (cART) HIV-positive patients with HIV Associated Neurocognitive Disorders (HAND) were enrolled to undergo a computer-based rehabilitation program (https://dynamicbrain.brainhq.com/) for 12 weeks, under the supervision of a physician. At the end (T1), the patients were tested again with a neuropsychological battery. Patient 1 (current CD4 T-cell count 405/mmc, HIV-RNA < 40UI/ml) had a diagnosis of mild neurocognitive disorders (MND) at T0 and normal evaluation at T1. Patient 2 (current CD4 T-cell count 366/mmc, HIV-RNA < 40UI/ml) had asymptomatic neurocognitive disorders (ANI) at T0 and normal performance at T1. Patient 3 (current CD4 T-cell count 522/mmc, HIV-RNA < 40UI/ml) had MND at T0 and normal performances at T1. Patients’ adherence to the program was 100%. Our pilot experience with a computer-based restorative approach showed good results in term of improvement in neuropsychological performances in treated HIV+ patients. These data suggest the need to explore innovative ways to manage HAND.
Cognitive Neuro-Rehabilitation of HIV-Associated Neurocognitive Disorders : Case Reports of A New Computer-Based Restorative Approach In 3 Hiv-Positive Cart-Treated Patients / F. Iannuzzi, F. Bai, L. Borghi, M. Trunfio, E. Vegni, A. d'Arminio Monforte, G. Marchetti. - In: JOURNAL OF NEUROPHYSIOLOGY AND NEUROLOGICAL DISORDERS. - ISSN 2375-2491. - 3(2016 Nov 22), pp. 1-5.
|Titolo:||Cognitive Neuro-Rehabilitation of HIV-Associated Neurocognitive Disorders : Case Reports of A New Computer-Based Restorative Approach In 3 Hiv-Positive Cart-Treated Patients|
IANNUZZI, FRANCESCA (Primo)
BAI, FRANCESCA (Secondo)
D'ARMINIO MONFORTE, ANTONELLA (Penultimo)
MARCHETTI, GIULIA CARLA (Ultimo)
|Settore Scientifico Disciplinare:||Settore M-PSI/08 - Psicologia Clinica|
Settore MED/17 - Malattie Infettive
|Data di pubblicazione:||22-nov-2016|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.17303/jnnd.2016.103|
|Appare nelle tipologie:||01 - Articolo su periodico|
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