The term 'Primary Cutaneous B-Cell Lymphoma' (PCBCL) comprehends a variety of lymphoproliferative disorders characterized by a clonal proliferation of B-cells primarily involving the skin. The absence of evident extra-cutaneous disease must be confirmed after six-month follow-up in order to exclude a nodal non-Hodgkin's lymphoma (NHL) with secondary cutaneous involvement, which may have a completely different clinical behavior and prognosis. In this article, we have summarized the clinico-pathological features of main types of PCBCL and we outline the guidelines for management based on a review of the available literature.
A literature revision in primary cutaneous B-cell lymphoma / R. La Selva, S. Alberti Violetti, C. Delfino, V. Grandi, S. Cicchelli, C. Tomasini, M.T. Fierro, E. Berti, N. Pimpinelli, P. Quaglino. - In: INDIAN JOURNAL OF DERMATOLOGY. - ISSN 0019-5154. - 62:2(2017 Mar 09), pp. 146-157. [10.4103/ijd.IJD_74_17]
A literature revision in primary cutaneous B-cell lymphoma
S. Alberti ViolettiSecondo
;E. Berti;
2017
Abstract
The term 'Primary Cutaneous B-Cell Lymphoma' (PCBCL) comprehends a variety of lymphoproliferative disorders characterized by a clonal proliferation of B-cells primarily involving the skin. The absence of evident extra-cutaneous disease must be confirmed after six-month follow-up in order to exclude a nodal non-Hodgkin's lymphoma (NHL) with secondary cutaneous involvement, which may have a completely different clinical behavior and prognosis. In this article, we have summarized the clinico-pathological features of main types of PCBCL and we outline the guidelines for management based on a review of the available literature.
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