The occurrence of blistering eruptions in childhood Henoch-Schönlein syndrome has been so far addressed exclusively in individual case reports. To describe epidemiology, clinical presentation, and therapeutic options in Henoch-Schönlein patients ≤18 years of age with blistering eruptions, we completed a systematic literature search. For the final analysis, we retained 39 reports. Ten children with blisters were found in 7 (1.5%) case series containing a total of 666 unselected pediatric Henoch-Schönlein cases. We also found 41 individually documented cases of Henoch-Schönlein syndrome with blistering eruptions. Blistering eruptions and purpura were distributed very similarly, blisters developed concomitantly with palpable purpura or with a latency of ≤14 days, and 80% of the cases remitted within 4 weeks with a similar course in children managed expectantly and in those managed with steroids.
Blistering eruptions in childhood Henoch-Schönlein syndrome : systematic review of the literature / V. Ramelli, S.A.G. Lava, G.D. Simonetti, M.G. Bianchetti, G.P. Ramelli, G.P. Milani. - In: EUROPEAN JOURNAL OF PEDIATRICS. - ISSN 0340-6199. - 176:4(2017 Apr), pp. 487-492.
|Titolo:||Blistering eruptions in childhood Henoch-Schönlein syndrome : systematic review of the literature|
MILANI, GREGORIO PAOLO (Ultimo)
|Parole Chiave:||Blister; Colchicine; Glucocorticoids; Purpura; Schönlein-Henoch; Vasculitis|
|Settore Scientifico Disciplinare:||Settore MED/38 - Pediatria Generale e Specialistica|
|Data di pubblicazione:||apr-2017|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1007/s00431-017-2858-3|
|Appare nelle tipologie:||01 - Articolo su periodico|