Despite left ventricular (LV) dysfunction contributing to mortality in chronic heart failure (HF), the molecular mechanisms of LV failure continues to remain poorly understood and myocardial biomarkers have yet to be identified. The aim of this pilot study was to investigate specific transcriptome changes occurring in cardiac tissues of patients with HF compared to healthy condition patients to improve diagnosis and possible treatment of affected subjects.
Heart failure: Pilot transcriptomic analysis of cardiac tissue by RNA-sequencing / C. Schiano, V. Costa, M. Aprile, V. Grimaldi, C. Maiello, R. Esposito, A. Soricelli, V. Colantuoni, F. Donatelli, A. Ciccodicola, C. Napoli. - In: CARDIOLOGY JOURNAL. - ISSN 1897-5593. - (2017 May 12). [10.5603/CJ.a2017.0052]
Heart failure: Pilot transcriptomic analysis of cardiac tissue by RNA-sequencing
F. Donatelli;
2017
Abstract
Despite left ventricular (LV) dysfunction contributing to mortality in chronic heart failure (HF), the molecular mechanisms of LV failure continues to remain poorly understood and myocardial biomarkers have yet to be identified. The aim of this pilot study was to investigate specific transcriptome changes occurring in cardiac tissues of patients with HF compared to healthy condition patients to improve diagnosis and possible treatment of affected subjects.File | Dimensione | Formato | |
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