Group A rotaviruses (RVA) are the leading cause of acute gastroenteritis (AGE) in young (aged <5 years) children, causing ∼250,000 deaths worldwide, mostly in developing countries. Differences on nucleotide sequences of VP7 (G-type) and VP4 (P-type) genes are the basis for the binary RVA nomenclature. Although at least 32 G-types and 47 P-types of rotavirus are presently known, most RVA infections in humans worldwide are related to five major G/P combinations: G1P[8], G2P[4], G3P[8], G4P[8], and G9P[8].
Group A rotavirus genotypes in hospital-acquired gastroenteritis in Italy, 2012-14 / G. Ianiro, R. Delogu, L. Fiore, M. Monini, F.M. Ruggeri, E. Pagani, L. Moroder, S. Binda, L. Pellegrinelli, A. Mignacca, R. Bruno, A. Vuolo, F. Zanella, G. Bordignon, P. Pietrosemoli, T. Lazzarotto, A. Chiereghin, A. Marigliano, B. Camilloni, C. Russo, R. Graffeo, M. Labianca, P. Castiglia. - In: THE JOURNAL OF HOSPITAL INFECTION. - ISSN 0195-6701. - 96:3(2017 Apr 08), pp. 262-267. [10.1016/j.jhin.2017.04.004]
Group A rotavirus genotypes in hospital-acquired gastroenteritis in Italy, 2012-14
S. Binda;L. Pellegrinelli;
2017
Abstract
Group A rotaviruses (RVA) are the leading cause of acute gastroenteritis (AGE) in young (aged <5 years) children, causing ∼250,000 deaths worldwide, mostly in developing countries. Differences on nucleotide sequences of VP7 (G-type) and VP4 (P-type) genes are the basis for the binary RVA nomenclature. Although at least 32 G-types and 47 P-types of rotavirus are presently known, most RVA infections in humans worldwide are related to five major G/P combinations: G1P[8], G2P[4], G3P[8], G4P[8], and G9P[8].
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