Objective: Involvement of the pancreato-biliary system has been occasionally noted in Henoch-Schonlein purpura. Furthermore, cases of this vasculitis syndrome sometimes develop in the context of a viral hepatitis or after hepatitis vaccination. Methods: We completed a review of the literature. Results: Fifty reports published between 1977 and 2015 were retained for the analysis. A pancreato-biliary involvement was recognized in 34 individually well-described patients (O=19:15) with severe abdominal pain: pancreatitis (N=20), acalculous cholecystitis (N=11), both pancreatitis and cholecystitis (N=3). In all of the pancreatitis patients, full recovery occurred (within 3 weeks in three-fourths of the patients). Cholecystectomy was performed in 8 cholecystitis patients. Seventeen Henoch-Schonlein patients (O=9:8) were associated with a viral liver disease and 4 (O=1:3) with a hepatitis vaccination. The vasculitis syndrome rapidly remitted in the 7 patients accompanying hepatitis A or E, in 2 patients of hepatitis B, and in the 4 patients preceded by a vaccination. Henoch-Schonlein purpura seemed to be serious in 5 patients with chronic hepatitis B and in 3 with chronic hepatitis C. Conclusions: This analysis indicates that pancreato-biliary involvement is unusual in Henoch-Schonlein purpura. This complication deserves consideration in patients with especially severe abdominal pain. Finally, viral hepatitides and hepatitis vaccinations seem to be rare triggers of Henoch-Schonlein purpura.
Gallbladder and pancreas in henoch-schonlein purpura : Review of the literature / R. Helbling, S.A.G. Lava, G.D. Simonetti, P. Camozzi, M.G. Bianchetti, G.P. Milani. - In: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. - ISSN 0277-2116. - 62:3(2016 Mar), pp. 457-461. [10.1097/MPG.0000000000000955]
Gallbladder and pancreas in henoch-schonlein purpura : Review of the literature
G.P. MilaniUltimo
2016
Abstract
Objective: Involvement of the pancreato-biliary system has been occasionally noted in Henoch-Schonlein purpura. Furthermore, cases of this vasculitis syndrome sometimes develop in the context of a viral hepatitis or after hepatitis vaccination. Methods: We completed a review of the literature. Results: Fifty reports published between 1977 and 2015 were retained for the analysis. A pancreato-biliary involvement was recognized in 34 individually well-described patients (O=19:15) with severe abdominal pain: pancreatitis (N=20), acalculous cholecystitis (N=11), both pancreatitis and cholecystitis (N=3). In all of the pancreatitis patients, full recovery occurred (within 3 weeks in three-fourths of the patients). Cholecystectomy was performed in 8 cholecystitis patients. Seventeen Henoch-Schonlein patients (O=9:8) were associated with a viral liver disease and 4 (O=1:3) with a hepatitis vaccination. The vasculitis syndrome rapidly remitted in the 7 patients accompanying hepatitis A or E, in 2 patients of hepatitis B, and in the 4 patients preceded by a vaccination. Henoch-Schonlein purpura seemed to be serious in 5 patients with chronic hepatitis B and in 3 with chronic hepatitis C. Conclusions: This analysis indicates that pancreato-biliary involvement is unusual in Henoch-Schonlein purpura. This complication deserves consideration in patients with especially severe abdominal pain. Finally, viral hepatitides and hepatitis vaccinations seem to be rare triggers of Henoch-Schonlein purpura.File | Dimensione | Formato | |
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