A 21-month-old boy came to our attention because of pneumonia. His weight increased before presentation, and his blood test results showed hyponatremia (116 mEq/L), low plasma osmolarity (241 mOsm/L), and high urine osmolarity (435 mOsm/L). He was treated with 0.9% sodium chloride solution and intravenous furosemide, and sodium levels rose up to 135 mEq/L in 36 hours. No standard treatment is available for severe hyponatremia in children. The use of vaptans in pediatric patients is described in literature, but it lacks evidence about safety and effectiveness. We suggest that furosemide administration plus salt replacement is effective in restoring normal values of plasma sodium concentration in severe euvolemic and hypervolemic hyponatremia.

Treatment of Severe Hypervolemic Hyponatremia in a Child with Pneumonia / T. Genoni, R. Tenconi, G. Bertolozzi, E.A. Laicini, G. Tardini, F. Vianello, E. Leva, G.P. Milani, E.F. Fossali. - In: PEDIATRIC EMERGENCY CARE. - ISSN 0749-5161. - 32:6(2016 Jun), pp. 390-391. [10.1097/PEC.0000000000000823]

Treatment of Severe Hypervolemic Hyponatremia in a Child with Pneumonia

T. Genoni;R. Tenconi;F. Vianello;E. Leva;G.P. Milani;
2016-06

Abstract

A 21-month-old boy came to our attention because of pneumonia. His weight increased before presentation, and his blood test results showed hyponatremia (116 mEq/L), low plasma osmolarity (241 mOsm/L), and high urine osmolarity (435 mOsm/L). He was treated with 0.9% sodium chloride solution and intravenous furosemide, and sodium levels rose up to 135 mEq/L in 36 hours. No standard treatment is available for severe hyponatremia in children. The use of vaptans in pediatric patients is described in literature, but it lacks evidence about safety and effectiveness. We suggest that furosemide administration plus salt replacement is effective in restoring normal values of plasma sodium concentration in severe euvolemic and hypervolemic hyponatremia.
diuretics; hyponatremia; intravenous fluids; diagnosis, differential; diuretics; fluid therapy; furosemide; humans; hyponatremia; inappropriate adh syndrome; infant; male; pneumonia; pediatrics, perinatology and child health; emergency medicine
Settore MED/38 - Pediatria Generale e Specialistica
PEDIATRIC EMERGENCY CARE
Article (author)
File in questo prodotto:
File Dimensione Formato  
GenoniFossali_PediatricEmergencyCare_TreatmentSevere_2016.pdf

non disponibili

103.43 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/489350
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 2
  • ???jsp.display-item.citation.isi??? 2
social impact