It has been estimated that 35 million people worldwide and 0.2% of Italian population has a chronic HIV-1 infection. The use of antiretroviral drugs has provided a noteworthy improvement in both the quality and the expectancy of life of people infected with HIV; therefore, as three quarters of infected people are in their reproductive years, many couples with an HIV positive partner can consider pregnancy planning. The aims of this study were twofold: the first aim was to assess the effect of HIV-1 infection on semen parameters; the second aim was to evaluate the effects of highly active antiretroviral therapy (HAART) on sperm DNA fragmentation comparing HIV-1 infected patients receiving HAART versus naïve HIV-1 infected patients.
Effects of HIV-1 infection and antiretroviral therapy on semen parameters and sperm DNA integrity / V. Savasi, A. Laoreti, B. Parrilla, M. Oneta, M. Musto, I. Cetin. ((Intervento presentato al convegno SIMP tenutosi a Assisi nel 2015.
Effects of HIV-1 infection and antiretroviral therapy on semen parameters and sperm DNA integrity
V. Savasi;A. Laoreti;I. Cetin
2015
Abstract
It has been estimated that 35 million people worldwide and 0.2% of Italian population has a chronic HIV-1 infection. The use of antiretroviral drugs has provided a noteworthy improvement in both the quality and the expectancy of life of people infected with HIV; therefore, as three quarters of infected people are in their reproductive years, many couples with an HIV positive partner can consider pregnancy planning. The aims of this study were twofold: the first aim was to assess the effect of HIV-1 infection on semen parameters; the second aim was to evaluate the effects of highly active antiretroviral therapy (HAART) on sperm DNA fragmentation comparing HIV-1 infected patients receiving HAART versus naïve HIV-1 infected patients.
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