Aims: To evaluate technical issues and clinical outcomes after postoperative volumetric-modulated arc therapy (VMAT) in two cases of malignant lacrimal gland cancer. Patients & methods: Patients were treated by postoperative VMAT and post-treatment clinical outcomes were followed-up to 18 months. Results: Dosimetric results were acceptable and acute toxicity was manageable in both patients. No evidence of disease was found at latest follow-up. One patient underwent corneal transplant for central corneal ulceration, experiencing reduction of visual acuity. Conclusion: Postoperative VMAT for treatment of lacrimal gland tumors offers improved outcome, with manageable side effects. In the context of photon beam radiotherapy, VMAT emerged as a valuable treatment option for these malignant tumors.
Postoperative radiotherapy with volumetric modulated arc therapy of lacrimal gland carcinoma : Two case reports and literature review / E. Orlandi, S. Takanen, T. Giandini, E. Iannacone, W. Fontanella, L. Locati, M. Carrara, P. Bossi, C. Bergamini, R. Granata, V. Tombolini, T. Ibba, L. Licitra, E. Pignoli, C. Fallai. - In: FUTURE ONCOLOGY. - ISSN 1082-331X. - 10:14(2014 Nov), pp. 2111-2120. [10.2217/fon.14.148]
Postoperative radiotherapy with volumetric modulated arc therapy of lacrimal gland carcinoma : Two case reports and literature review
L. Licitra;
2014
Abstract
Aims: To evaluate technical issues and clinical outcomes after postoperative volumetric-modulated arc therapy (VMAT) in two cases of malignant lacrimal gland cancer. Patients & methods: Patients were treated by postoperative VMAT and post-treatment clinical outcomes were followed-up to 18 months. Results: Dosimetric results were acceptable and acute toxicity was manageable in both patients. No evidence of disease was found at latest follow-up. One patient underwent corneal transplant for central corneal ulceration, experiencing reduction of visual acuity. Conclusion: Postoperative VMAT for treatment of lacrimal gland tumors offers improved outcome, with manageable side effects. In the context of photon beam radiotherapy, VMAT emerged as a valuable treatment option for these malignant tumors.File | Dimensione | Formato | |
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