The PRDC is a multifactorial respiratory syndrome supported by various pathogens that play a defined and recognized role. The severity of clinical manifestations also depends on conditioning factors of non-infectious nature, linked to the farming situations. The interference on production and health depends on the loss of the fragile balance between the infectious pressure and the organic resistance of pigs. The latter depends on the immune efficiency of pigs and group against pathogens and their interactions. In this perspective, the mechanisms of the response to each of them were considered separately. The effects of immune impairment and immuno-modulation that are the basis of the interactions were especially analyzed. For each pathogen, the mechanisms of the immune response were also characterized.
La PRDC è una sindrome respiratoria polifattoriale sostenuta da diversi patogeni che svolgono un ruolo definito e riconosciuto. Alla gravità delle manifestazioni cliniche contribuiscono i fattori condizionanti di natura non infettiva, dipendenti dalle situazioni di allevamento. Il danno produttivo e sanitario dipende dalla perdita dell’equilibrio, molto fragile, tra la pressione infettante e la resistenza organica dei suini; quest’ultima, dipende dall’efficienza immunitaria dei singoli e del gruppo nei confronti dei patogeni e delle loro interazioni. In questa prospettiva, sono stati considerati singolarmente i patogeni partecipanti alla sindrome e i meccanismi della risposta a ciascuno di essi, analizzando soprattutto gli effetti d’immuno-compromissione e immuno-modulazione che sono alla base delle interazioni. Per ciascun agente patogeno sono stati inoltre caratterizzati i meccanismi della risposta immunitaria.
Patogeni respiratori e immunità = Immune response in PRDC / V. Sala. - In: SUMMA ANIMALI DA REDDITO. - ISSN 1828-5546. - 11:7(2016 Sep), pp. 61-66.
Patogeni respiratori e immunità = Immune response in PRDC
V. Sala
2016
Abstract
The PRDC is a multifactorial respiratory syndrome supported by various pathogens that play a defined and recognized role. The severity of clinical manifestations also depends on conditioning factors of non-infectious nature, linked to the farming situations. The interference on production and health depends on the loss of the fragile balance between the infectious pressure and the organic resistance of pigs. The latter depends on the immune efficiency of pigs and group against pathogens and their interactions. In this perspective, the mechanisms of the response to each of them were considered separately. The effects of immune impairment and immuno-modulation that are the basis of the interactions were especially analyzed. For each pathogen, the mechanisms of the immune response were also characterized.File | Dimensione | Formato | |
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