BACKGROUND: The aim of this study is to compare intra-operative cultural examination in patients undergoing elective surgery for low-back pain with Modic 2 changes to patients without Modic signs. The aim of this study is to compare intra-operative cultural examination in patients undergoing elective surgery for low-back pain with Modic 2 changes to patients without Modic signs. METHODS: Sixteen patients with Modic 2 changes were compared with 23 patients without Modic signs. Pre-operative laboratory tests and intra-operative tissue cultures were performed, according to a standardized procedure. RESULTS: While no difference was found in pre-operative laboratory tests, intra-operative cultural examination showed positive results in 6/16 (37.5%) Modic 2 patients versus 1/23 (4.3%) in patients without Modic changes (P=0.012). CONCLUSIONS: Although performed in a limited series of patients, this study supports the hypothesis that some cases of Modic 2 changes might be associated with the presence of low virulent bacteria.
Are MODIC Type 2 disc changes associated with low-grade infections? : A pilot study / L. Drago, C.L. Romanò, R. Cecchinato, J.H. Villafañe, E. De Vecchi, C. Lamartina, P. Berjano. - In: JOURNAL OF NEUROSURGICAL SCIENCES. - ISSN 0390-5616. - (2017 Feb 15). [Epub ahead of print]
Are MODIC Type 2 disc changes associated with low-grade infections? : A pilot study
L. DragoPrimo
;R. Cecchinato;E. De Vecchi;
2017
Abstract
BACKGROUND: The aim of this study is to compare intra-operative cultural examination in patients undergoing elective surgery for low-back pain with Modic 2 changes to patients without Modic signs. The aim of this study is to compare intra-operative cultural examination in patients undergoing elective surgery for low-back pain with Modic 2 changes to patients without Modic signs. METHODS: Sixteen patients with Modic 2 changes were compared with 23 patients without Modic signs. Pre-operative laboratory tests and intra-operative tissue cultures were performed, according to a standardized procedure. RESULTS: While no difference was found in pre-operative laboratory tests, intra-operative cultural examination showed positive results in 6/16 (37.5%) Modic 2 patients versus 1/23 (4.3%) in patients without Modic changes (P=0.012). CONCLUSIONS: Although performed in a limited series of patients, this study supports the hypothesis that some cases of Modic 2 changes might be associated with the presence of low virulent bacteria.Pubblicazioni consigliate
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