Purpose of Review Viscosupplementation (VS) is the intra-articular administration of hyaluronic acid (HA) to treat joint osteoarthritis (OA), with the aim of lubricating intra-articular space and promote viscoinduction. In this article we reviewed the latest scientific evidence on VS for the treatment of symptomatic OA. Recent Findings Despite the use of HA intra-articular injections for treating OA is growing, some controversial aspects about its efficacy and cost-effectiveness remain. Apart for knee, medical evidence is still sparse for most of the joint. These contradictory results from meta-analysis led several international societies to produce guidelines with conflicting recommendations. Summary Whereas HA intra-articular injections are now considered effective and safe for mild to moderate knee OA, its utility in other joint is still questioned and matter of debate. Further prospective studies are warranted for a better understanding of VS clinical and molecular efficacy.

The Role of Joint Viscosupplementation in Geriatric Population / C. Messina, G. Guglielmi, D. Orlandi, A. Corazza, G. Mauri, L.M. Sconfienza. - In: CURRENT RADIOLOGY REPORTS. - ISSN 2167-4825. - 5:1(2017 Jan 17), pp. 1-8. [10.1007/s40134-017-0196-x]

The Role of Joint Viscosupplementation in Geriatric Population

C. Messina
Primo
;
G. Mauri
Penultimo
;
L.M. Sconfienza
Ultimo
2017

Abstract

Purpose of Review Viscosupplementation (VS) is the intra-articular administration of hyaluronic acid (HA) to treat joint osteoarthritis (OA), with the aim of lubricating intra-articular space and promote viscoinduction. In this article we reviewed the latest scientific evidence on VS for the treatment of symptomatic OA. Recent Findings Despite the use of HA intra-articular injections for treating OA is growing, some controversial aspects about its efficacy and cost-effectiveness remain. Apart for knee, medical evidence is still sparse for most of the joint. These contradictory results from meta-analysis led several international societies to produce guidelines with conflicting recommendations. Summary Whereas HA intra-articular injections are now considered effective and safe for mild to moderate knee OA, its utility in other joint is still questioned and matter of debate. Further prospective studies are warranted for a better understanding of VS clinical and molecular efficacy.
Viscosupplementation; Hyaluronic acid; Osteoarthritis; Intra-articular injection; Hyaluronan Geriatrics
Settore MED/36 - Diagnostica per Immagini e Radioterapia
17-gen-2017
Article (author)
File in questo prodotto:
File Dimensione Formato  
Curr Rad Report Messina et al 2017.pdf

accesso riservato

Tipologia: Publisher's version/PDF
Dimensione 531.39 kB
Formato Adobe PDF
531.39 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/471692
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 3
  • ???jsp.display-item.citation.isi??? ND
social impact