The Arp2/3 complex is essential for actin nucleation and filament elongation in a variety of intracellular processes. This functional versatility is exerted through the regulation of its activity by nucleation-promoting factors (NPFs). The discovery of a new NPF, WHAMM, reveals unexpected connections between the actin and microtubule cytoskeletons and membrane dynamics during ER-to-Golgi transport
Cytoskeletal regulation : coordinating actin and microtubule dynamics in membrane trafficking [Recensione] / A. Disanza, G. Scita. - In: CURRENT BIOLOGY. - ISSN 0960-9822. - 18:18(2008 Sep 23), pp. R873-R875.
Cytoskeletal regulation : coordinating actin and microtubule dynamics in membrane trafficking
A. Disanza;G. ScitaUltimo
2008
Abstract
The Arp2/3 complex is essential for actin nucleation and filament elongation in a variety of intracellular processes. This functional versatility is exerted through the regulation of its activity by nucleation-promoting factors (NPFs). The discovery of a new NPF, WHAMM, reveals unexpected connections between the actin and microtubule cytoskeletons and membrane dynamics during ER-to-Golgi transport
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