• Candida spp. is the most common cause of intensive care unit (ICU) invasive fungal infections worldwide. • The isolation of Candida spp. from respiratory tract secretions of non-immunocompromised, mechanically ventilated patients varies between 20% and 55%, but it might represent colonisation rather than infection. • Candida spp. colonisation promotes bacterial pneumonia in animal models. • Candida spp. colonisation could clinically increase the risk for Pseudomonas aeruginosa ventilator-associated pneumonia, prolong mechanical ventilation and stay and worsen outcomes, but to date contrasting data are available. • Available evidence is not sufficient to support routine antifungal therapy in non-immunocompromised patients.
Candida Spp. in the respiratory tract : a real causality with worse outcomes or just a marker of severity? / S. Terraneo, M. Ferrer, A. Torres. - In: ICU MANAGEMENT. - ISSN 1783-2470. - 16:3(2016), pp. 158-160.
|Titolo:||Candida Spp. in the respiratory tract : a real causality with worse outcomes or just a marker of severity?|
TERRANEO, SILVIA (Primo)
|Settore Scientifico Disciplinare:||Settore MED/10 - Malattie dell'Apparato Respiratorio|
|Data di pubblicazione:||2016|
|Appare nelle tipologie:||01 - Articolo su periodico|