Cocaine is a drug with relevant socioeconomic and clinical implications, which is usually recreationally used for its stimulant effects. It is widely known that the habit of snorting cocaine is associated with a peculiar type of drug-induced chronic rhinitis, which leads to inflammation of the sinonasal mucosa, slowly progressing to a destruction of nasal, palatal and pharyngeal tissues. These characteristic lesions due to cocaine abuse are commonly called cocaine-induced midline destructive lesions (CIMDL). Diagnosis is not always straightforward, since various conditions, mainly vasculitis, might mimic this acquired condition. The extent of pharyngeal involvement varies, although often a prolonged abuse can trigger a progressive destruction of oral and nasal tissues, with development of infections and recurrent inflammation. Our article focuses on cocaine as a world health problem with important ear, nose and throat implications and discusses the difficulties in diagnosing and treating CIMDL, through a case report.
Snorting the clivus away : An extreme case of cocaine-induced midline destructive lesion / M. Molteni, A.M. Saibene, K. Luciano, A. Maccari. - In: BMJ CASE REPORT. - ISSN 1757-790X. - 2016(2016).
|Titolo:||Snorting the clivus away : An extreme case of cocaine-induced midline destructive lesion|
SAIBENE, ALBERTO MARIA (Corresponding)
|Parole Chiave:||medicine (all)|
|Settore Scientifico Disciplinare:||Settore MED/31 - Otorinolaringoiatria|
|Data di pubblicazione:||2016|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1136/bcr-2016-216393|
|Appare nelle tipologie:||01 - Articolo su periodico|