A 6-month-old female infant considered to be in good health died suddenly and unexpectedly. Post-mortem examination was requested, with clinical diagnosis of sudden infant death syndrome. Gross examination revealed, however, the presence of a cardiac mass 4.5 X 4 x 3.5 cm in diameter. Histological examination of the heart confirmed the presence of a cardiac fibroma. In the present case, the sudden death could have been due to the left ventricular outflow obstruction, as much as to conductive disturbances caused by overstretching and compression of the atrioventricular node and of the bundle branches. Hemodynamic and conductive abnormalities are presumed to have provoked bradycardia degenerating into ventricular fibrillation and sudden death. Necroscopy studies of sudden death should always include histological examination of the cardiac conduction system but seldom do.
|Titolo:||Pathology of the heart and conduction system in a case of sudden death due to a cardiac fibroma in a 6-month-old child|
|Parole Chiave:||Cardiac fibroma ; heart pathology ; cardiac conduction system|
|Settore Scientifico Disciplinare:||Settore MED/08 - Anatomia Patologica|
|Data di pubblicazione:||mar-1999|
|Digital Object Identifier (DOI):||10.1016/S1054-8807(98)00030-1|
|Appare nelle tipologie:||01 - Articolo su periodico|