The aim of our study was to compare, using near-infrared spectroscopy (NIRS), the effects on cerebral intracellular oxygenation and cerebral blood volume (CBV) of closed endotracheal suctioning (CS), which permits continuous ventilation of the patient, with open endotracheal suctioning (OS), which requires disconnection from the ventilator. Eleven preterm infants were studied. Each patient underwent one CS, followed, after 60 min, by one OS, or vice versa, three times during the same day. Modifications in CBV and oxidized cytochrome oxidase (CytO2) were continuously detected by NIRS; arterial oxygen saturation (SaO2) heart rate (HR), transcutaneous carbon dioxide tension and mean arterial blood pressure were simultaneously recorded. Significant reductions in HR and SaO2 were observed following OS; the magnitude and duration of these negative effects of suctioning were significantly reduced with CS. In addition, the decrease in CBV was more pronounced than following CS. No changes in CytO2 concentration were seen.
Closed versus open endotracheal suctioning in preterm infants: effects on cerebral oxygenation and blood volume / F.A. Mosca, M. Colnaghi, M. Lattanzio, M. Bray, S. Pugliese, M. Fumagalli. - In: BIOLOGY OF THE NEONATE. - ISSN 0006-3126. - 72:1(1997), pp. 9-14.
|Titolo:||Closed versus open endotracheal suctioning in preterm infants: effects on cerebral oxygenation and blood volume|
COLNAGHI, MARIAROSA (Secondo)
PUGLIESE, SILVIA (Penultimo)
FUMAGALLI, MONICA (Ultimo)
|Parole Chiave:||endotracheal suctioning; cerebral hemodynamics; cerebral oxygenation; preterm infants; near-infrared spectroscopy|
|Settore Scientifico Disciplinare:||Settore MED/38 - Pediatria Generale e Specialistica|
|Data di pubblicazione:||1997|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1159/000244460|
|Appare nelle tipologie:||01 - Articolo su periodico|