The paper underlines the application of new approaches that, linking gene profiling and functional results with high-throughput data and predictive bioinformatics, allow the characterization of biomolecular pathways and putative disease-related genes. This strategy will be a useful tool to identify the genes involved in the pathogenesis of the still large amount of idiopathic forms of Kallmann's and other genetic diseases.
F1000Prime Recommendation of [Garaffo G et al., Front Endocrinol (Lausanne) 2013, 4:203] / R. Maggi. - (2016 Nov 02). [10.3410/f.718240354.793524926]
F1000Prime Recommendation of [Garaffo G et al., Front Endocrinol (Lausanne) 2013, 4:203]
R. Maggi
2016
Abstract
The paper underlines the application of new approaches that, linking gene profiling and functional results with high-throughput data and predictive bioinformatics, allow the characterization of biomolecular pathways and putative disease-related genes. This strategy will be a useful tool to identify the genes involved in the pathogenesis of the still large amount of idiopathic forms of Kallmann's and other genetic diseases.
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