This is the first reported case of 2 biofilm-producing bacteria, Staphylococcus aureus and Proteus mirabilis, identified from an aortic valve using an innovative device with dithiothreitol solution, able to dislodge bacterial biofilm. The method is usable in the operating theatre and recommended in infective endocarditis nonresponders to empiric therapy.
Use of Dithiothreitol to Dislodge Bacteria From the Biofilm on an Aortic Valve in the Operating Theatre : A Case of Infective Endocarditis Caused by Staphylococcus aureus and Proteus mirabilis / S.G. Rimoldi, E. De Vecchi, C. Pagani, A. Zambelli, A. Di Gregorio, E. Bosisio, P. Vanelli, R. Scrofani, M.R. Gismondo, G. Cagnoni, C. Antona. - In: THE ANNALS OF THORACIC SURGERY. - ISSN 1552-6259. - 102:4(2016 Oct), pp. e357-e359. [10.1016/j.athoracsur.2016.03.023]
Use of Dithiothreitol to Dislodge Bacteria From the Biofilm on an Aortic Valve in the Operating Theatre : A Case of Infective Endocarditis Caused by Staphylococcus aureus and Proteus mirabilis
S.G. Rimoldi;E. De VecchiSecondo
;C. Pagani;A. Di Gregorio;E. Bosisio;M.R. Gismondo;C. AntonaUltimo
2016
Abstract
This is the first reported case of 2 biofilm-producing bacteria, Staphylococcus aureus and Proteus mirabilis, identified from an aortic valve using an innovative device with dithiothreitol solution, able to dislodge bacterial biofilm. The method is usable in the operating theatre and recommended in infective endocarditis nonresponders to empiric therapy.
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