An 8-year-old spayed female cross-breed dog was evaluated following a 2-month history of thoracic limb weakness. Neurological examination revealed a spinal cord lesion between C1 and C5 segments. Magnetic resonance imaging (MRI) revealed that almost 70% of the spinal canal between C1 and C2 was occupied by an intradural extramedullary mass that was connected to a paraspinal mass from the cranial aspect of C2 to the cranial aspect of C3. The dog was anaesthetised and a dorsal, right-sided hemilaminectomy was performed. A durotomy was performed to expose a multilobular mass located principally along the right dorsal-lateral aspect of the spinal cord. The mass did not appear to infiltrate the cord parenchyma. The abnormal tissue was removed as completely as possible using gentle dissection and submitted for histological evaluation. The histological findings were consistent with an intradural-extramedullary haemangioblastoma with paraspinal extension. Following surgery, no neurological deterioration was detected. A metronomic-dosing chemotherapy protocol was administered to prevent progression or recurrence of the tumour. Follow-up MRI studies were performed 3, 6 and 12 months after the surgery, confirming complete tumour removal and the absence of recurrence.
Intradural-extramedullary haemangioblastoma with paraspinal extension in a dog / D. Binanti, D. De Zani, E. Fantinato, G. Allevi, G. Sironi, D.D. Zani. - In: AUSTRALIAN VETERINARY JOURNAL. - ISSN 0005-0423. - 93:12(2015 Dec), pp. 460-465.
|Titolo:||Intradural-extramedullary haemangioblastoma with paraspinal extension in a dog|
BINANTI, DIANA (Primo)
DE ZANI, DONATELLA (Secondo)
SIRONI, GIUSEPPE (Penultimo)
ZANI, DAVIDE DANILO (Ultimo)
|Parole Chiave:||dogs; haemangioblastoma; immunohistochemistry; magnetic resonance imaging; spinal neoplasm|
|Settore Scientifico Disciplinare:||Settore VET/03 - Patologia Generale e Anatomia Patologica Veterinaria|
Settore VET/09 - Clinica Chirurgica Veterinaria
|Data di pubblicazione:||dic-2015|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1111/avj.12376|
|Appare nelle tipologie:||01 - Articolo su periodico|
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