Regular exercise offers protection against all-cause mortality, primarily by protection against atherosclerosis and insulin resistance. There is evidence that physical training is effective as a treatment in patients with chronic heart diseases and type 2 diabetes. With excessive repetition of the training stimulus, local inflammation can generate a systemic inflammatory response. Cytokines play an important role in these processes. Our data confirm that cytokines that are considered to induce systemic bioactivity following exercise are not alone, but also growth factors and chemokines, which are secreted in exercise without the involvement of traditional proinflammatory cytokines, could be potent angiogenic factors.

Strenuous exercise activates growth factors and chemokines over-expression in human serum of top-level triathlon athletes during a competitive season / G. Banfi, S. Migliorini, F. Pedroni, E. Galliera, G. Dogliotti, A.E. Malavazos, M.M. Corsi. - In: CLINICAL CHEMISTRY AND LABORATORY MEDICINE. - ISSN 1434-6621. - 46:2(2008 Feb), pp. 250-252.

Strenuous exercise activates growth factors and chemokines over-expression in human serum of top-level triathlon athletes during a competitive season

G. Banfi
Primo
;
E. Galliera;G. Dogliotti;A.E. Malavazos
Penultimo
;
M.M. Corsi
Ultimo
2008-02

Abstract

Regular exercise offers protection against all-cause mortality, primarily by protection against atherosclerosis and insulin resistance. There is evidence that physical training is effective as a treatment in patients with chronic heart diseases and type 2 diabetes. With excessive repetition of the training stimulus, local inflammation can generate a systemic inflammatory response. Cytokines play an important role in these processes. Our data confirm that cytokines that are considered to induce systemic bioactivity following exercise are not alone, but also growth factors and chemokines, which are secreted in exercise without the involvement of traditional proinflammatory cytokines, could be potent angiogenic factors.
Settore MED/05 - Patologia Clinica
Settore BIO/12 - Biochimica Clinica e Biologia Molecolare Clinica
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/45049
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