We report the cytogenetic analysis of five cases of follicular thyroid adenoma. In two of them, we observed an identical t(2;3)(q12-13;p24-25) as a unique chromosome change. A third case showed a hyperdiploid karyotype with trisomies of chromosomes 7 and 12. Two cases had a normal diploid karyotype. These changes could define subgroups of follicular adenomas endowed with different malignant potential.
A t(2;3)(q12-13;p24-25) in follicular thyroid adenomas / G. Sozzi, M. Miozzo, T.C. Cariani, I. Bongarzone, S. Pilotti, M.A. Pierotti, G. Della Porta. - In: CANCER GENETICS AND CYTOGENETICS. - ISSN 0165-4608. - 64:1(1992 Nov), pp. 38-41.
A t(2;3)(q12-13;p24-25) in follicular thyroid adenomas
M. MiozzoSecondo
;
1992
Abstract
We report the cytogenetic analysis of five cases of follicular thyroid adenoma. In two of them, we observed an identical t(2;3)(q12-13;p24-25) as a unique chromosome change. A third case showed a hyperdiploid karyotype with trisomies of chromosomes 7 and 12. Two cases had a normal diploid karyotype. These changes could define subgroups of follicular adenomas endowed with different malignant potential.
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