An estimated 20% to 30% of all neuroendocrine tumours originate in the bronchial tree and lungs. According to the 2015 World Health Organization categorization, these tumours are separated into four subtypes characterized by increasing biological aggressiveness: typical carcinoid, atypical carcinoid, large-cell neuroendocrine carcinoma and small-cell carcinoma. Although typical and atypical lung carcinoids account for less than 1-5% of all pulmonary malignancies, the incidence of these neoplasms has risen significantly in recent decades. Surgery is the treatment of choice for loco-regional disease but for advanced lung carcinoids there is no recognized standard of care and successful management requires a multidisciplinary approach. The aim of this review is to provide a useful guide for the clinical management of lung carcinoids.
Diagnosis and management of typical and atypical lung carcinoids / S. Pusceddu, G. Lo Russo, M. Macerelli, C. Proto, M. Vitali, D. Signorelli, M. Ganzinelli, P. Scanagatta, L. Duranti, A. Trama, R. Buzzoni, G. Pelosi, U. Pastorino, F. de Braud, M.C. Garassino. - In: CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. - ISSN 1040-8428. - 100(2016 Apr), pp. 167-176.
Titolo: | Diagnosis and management of typical and atypical lung carcinoids | |
Autori: | PUSCEDDU, SARA (Primo) DE BRAUD, FILIPPO GUGLIELMO MARIA (Penultimo) | |
Parole Chiave: | atypical carcinoids; lung carcinoids; neuroendocrine tumours; typical carcinoids; oncology; hematology; geriatrics and gerontology | |
Settore Scientifico Disciplinare: | Settore MED/06 - Oncologia Medica | |
Data di pubblicazione: | apr-2016 | |
Rivista: | ||
Tipologia: | Article (author) | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/j.critrevonc.2016.02.009 | |
Appare nelle tipologie: | 01 - Articolo su periodico |
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