Digital ulcers (DUs) are a severe and frequent clinical feature of patients with systemic sclerosis (SSc). The presence of DUs may cause severe pain and often lead to impairment of patient’s functional activities and health-related quality of life. Moreover, poor patient cooperation during the wound care procedure due to pain may be associated with a negative outcome of DU healing. Therefore, pain management has a key role in patients with SSc. These two case reports describe the effectiveness and safety of oxycodone/naloxone in patients with SSc complicated by painful chronic DUs. Such a therapy has provided pain relief and consequently an increased compliance during redressing wounds.
Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers : Two case reports / N. Ughi, C. Crotti, F. Ingegnoli. - In: CLINICAL INTERVENTIONS IN AGING. - ISSN 1178-1998. - 11(2016), pp. 307-311.
|Titolo:||Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers : Two case reports|
UGHI, NICOLA (Primo)
CROTTI, CHIARA (Secondo)
INGEGNOLI, FRANCESCA ANNA (Corresponding)
|Parole Chiave:||analgaesia; calcinosis; digital ulcer; naloxone; opioids; oxycodone; pain; scleroderma; systemic sclerosis; ucla-sctc git 2.0; wound healing; administration, oral; aged; analgesics, opioid; chronic pain; drug therapy, combination; female; fingers; humans; middle aged; naloxone; oxycodone; pain management; quality of life; scleroderma, systemic; skin ulcer; wound healing; geriatrics and gerontology|
|Settore Scientifico Disciplinare:||Settore MED/16 - Reumatologia|
|Data di pubblicazione:||2016|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.2147/CIA.S102577|
|Appare nelle tipologie:||01 - Articolo su periodico|
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