Digital ulcers (DUs) are a severe and frequent clinical feature of patients with systemic sclerosis (SSc). The presence of DUs may cause severe pain and often lead to impairment of patient’s functional activities and health-related quality of life. Moreover, poor patient cooperation during the wound care procedure due to pain may be associated with a negative outcome of DU healing. Therefore, pain management has a key role in patients with SSc. These two case reports describe the effectiveness and safety of oxycodone/naloxone in patients with SSc complicated by painful chronic DUs. Such a therapy has provided pain relief and consequently an increased compliance during redressing wounds.

Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers : Two case reports / N. Ughi, C. Crotti, F. Ingegnoli. - In: CLINICAL INTERVENTIONS IN AGING. - ISSN 1178-1998. - 11(2016), pp. 307-311. [10.2147/CIA.S102577]

Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers : Two case reports

N. Ughi
Primo
;
C. Crotti
Secondo
;
F. Ingegnoli
2016

Abstract

Digital ulcers (DUs) are a severe and frequent clinical feature of patients with systemic sclerosis (SSc). The presence of DUs may cause severe pain and often lead to impairment of patient’s functional activities and health-related quality of life. Moreover, poor patient cooperation during the wound care procedure due to pain may be associated with a negative outcome of DU healing. Therefore, pain management has a key role in patients with SSc. These two case reports describe the effectiveness and safety of oxycodone/naloxone in patients with SSc complicated by painful chronic DUs. Such a therapy has provided pain relief and consequently an increased compliance during redressing wounds.
analgaesia; calcinosis; digital ulcer; naloxone; opioids; oxycodone; pain; scleroderma; systemic sclerosis; ucla-sctc git 2.0; wound healing; administration, oral; aged; analgesics, opioid; chronic pain; drug therapy, combination; female; fingers; humans; middle aged; naloxone; oxycodone; pain management; quality of life; scleroderma, systemic; skin ulcer; wound healing; geriatrics and gerontology
Settore MED/16 - Reumatologia
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/440903
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