Weighing supported nanoparticles: Size-selected clusters as mass standards in nanometrology

We present a new approach to quantify the mass and 3D shape of nanoparticles on supports, using size-selected nanoclusters as mass standards in scanning transmission electron microscope. Through quantitative image intensity analysis, we show that the integrated high angle annular dark field intensities of size-selected gold clusters soft-landed on graphite display a monotonic dependence on the cluster size as far as ∼6500 atoms. We applied this mass standard to study gold nanoparticles prepared by thermal vapor deposition and by colloidal wet chemistry, and from which we deduced the shapes of these two types of nanoparticles as expected.