Malnutrition is common in alcoholic liver disease and is associated with high rates of complications and mortality. In this article, the current literature was reviewed to highlight the relevance of proper nutritional management providing levels of evidence, when available. A PubMed search was performed for English-language publications from 1980 through 2014 with the keywords: alcoholic liver disease, nutritional deficiencies, nutritional support, enteral nutrition, parenteral nutrition, and protein-energy malnutrition. Manuscripts focused on nutritional approach in patients with alcoholic liver disease were selected.Although nutritional support for malnourished patients improves the outcome of hospitalization, surgery, transplantation and reduces the complications of liver disease and the length of hospital stay, specific guidelines are scanty. Both enteral and parenteral nutrition appear to improve nutritional parameters and liver function; however data on survival is often conflicting. As micronutrient depletion is common in alcoholic liver disease and each deficiency produces specific sequelae, all cirrhotic patients should be screened at baseline for deficiencies of micronutrient and supplemented as needed.In summary, protein-energy malnutrition and micronutrient depletion are clinical concerns in alcoholic liver disease. Nutritional therapy, including enteral nutrition, parenteral nutrition and micronutrient supplementation should be part of the multidisciplinary management of these patients.
Diagnosis and treatment of nutritional deficiencies in alcoholic liver disease : overview of available evidence and open issues / R.E. Rossi, D. Conte, S. Massironi. - In: DIGESTIVE AND LIVER DISEASE. - ISSN 1590-8658. - 47:10(2015 Oct), pp. 819-825.
|Titolo:||Diagnosis and treatment of nutritional deficiencies in alcoholic liver disease : overview of available evidence and open issues|
ROSSI, ROBERTA ELISA (Primo)
CONTE, DARIO (Secondo)
MASSIRONI, SARA (Ultimo)
|Parole Chiave:||Alcoholic liver disease; Enteral nutrition; Nutritional deficiencies; Nutritional support; Parenteral nutrition; Protein-energy malnutrition; Humans; Length of Stay; Liver Diseases, Alcoholic; Malnutrition; Micronutrients; Nutritional Support; Severity of Illness Index; Enteral Nutrition; Parenteral Nutrition; Gastroenterology; Hepatology; Medicine (all)|
|Settore Scientifico Disciplinare:||Settore MED/12 - Gastroenterologia|
|Data di pubblicazione:||ott-2015|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1016/j.dld.2015.05.021|
|Appare nelle tipologie:||01 - Articolo su periodico|