Changes in the distribution and products of enteroendocrine cells may play a role in immune activation and regulation of gut inflammation. This review aims at critically evaluating the main enteroendocrine markers in inflammatory bowel diseases (IBD). A narrative review was performed by searching inflammatory bowel diseases and enteroendocrine biomarkers in PubMed. Relevant modifications of some enteroendocrine markers, such as Chromogranin A, and their correlation with disease activity have been reported in patients with inflammatory bowel diseases. Even if data about neuroendocrine markers are sometimes contrasting, they may be potentially useful for the diagnosis and clinical management of these patients.

Chromogranin A and other enteroendocrine markers in inflammatory bowel disease / S. Massironi, A. Zilli, F. Cavalcoli, D. Conte, M. Peracchi. - In: NEUROPEPTIDES. - ISSN 0143-4179. - 58(2016 Aug), pp. 127-134.

Chromogranin A and other enteroendocrine markers in inflammatory bowel disease

S. Massironi;A. Zilli;F. Cavalcoli;D. Conte;M. Peracchi
2016-08

Abstract

Changes in the distribution and products of enteroendocrine cells may play a role in immune activation and regulation of gut inflammation. This review aims at critically evaluating the main enteroendocrine markers in inflammatory bowel diseases (IBD). A narrative review was performed by searching inflammatory bowel diseases and enteroendocrine biomarkers in PubMed. Relevant modifications of some enteroendocrine markers, such as Chromogranin A, and their correlation with disease activity have been reported in patients with inflammatory bowel diseases. Even if data about neuroendocrine markers are sometimes contrasting, they may be potentially useful for the diagnosis and clinical management of these patients.
chromogranin a; crohn's disease; enteroendocrine cell; inflammatory bowel disease; ulcerative colitis; endocrinology; neurology; endocrine and autonomic systems; cellular and molecular neuroscience
Settore MED/12 - Gastroenterologia
NEUROPEPTIDES
Article (author)
File in questo prodotto:
File Dimensione Formato  
MassironiPeracchi_Neuropeptides_Cromogranin_2016.pdf

non disponibili

376.26 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/432860
Citazioni
  • ???jsp.display-item.citation.pmc??? 10
  • Scopus 17
  • ???jsp.display-item.citation.isi??? 15
social impact