Childhood obesity is a major global issue. Its incidence is constantly increasing, thereby offering a threatening public health perspective. The risk of developing the numerous chronic diseases associated with this condition from very early in life is significant. Although complex and multi-factorial, the pathophysiology of obesity recognizes essential roles of nutritional and metabolic aspects. Particularly, several risk factors identified as possible determinants of later-life obesity act within the first 1000 days of life (i.e., from conception to age 2 years). The purpose of this manuscript is to review those key mechanisms for which a role in predisposing children to obesity is supported by the most recent literature. Throughout the development of the human feeding environment, three different stages have been identified: (1) the prenatal period; (2) breast vs. formula feeding; and (3) complementary diet. A deep understanding of the specific nutritional challenges presented within each phase might foster the development of future preventive strategies.
Nutrition in the First 1000 Days : The Origin of Childhood Obesity / C. Mameli, S. Mazzantini, G.V. Zuccotti. - In: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. - ISSN 1660-4601. - 13:9(2016 Sep).
|Titolo:||Nutrition in the First 1000 Days : The Origin of Childhood Obesity|
MAMELI, CHIARA (Primo)
MAZZANTINI, SARA (Secondo)
ZUCCOTTI, GIAN VINCENZO (Ultimo)
|Parole Chiave:||breast feeding; child nutrition; diet; obesity; overweight|
|Settore Scientifico Disciplinare:||Settore MED/38 - Pediatria Generale e Specialistica|
|Data di pubblicazione:||set-2016|
|Data ahead of print / Data di stampa:||23-ago-2016|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.3390/ijerph13090838|
|Appare nelle tipologie:||01 - Articolo su periodico|
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