RANKS is a flexible software package that can be easily applied to any bioinformatics task formalizable as ranking of nodes with respect to a property given as a label, such as automated protein function prediction, gene disease prioritization and drug repositioning. To this end RANKS provides an efficient and easy-to-use implementation of kernelized score functions, a semi-supervised algorithmic scheme embedding both local and global learning strategies for the analysis of biomolecular networks. To facilitate comparative assessment, baseline network-based methods, e.g. label propagation and random walk algorithms, have also been implemented.

RANKS : a flexible tool for node label ranking and classification in biological networks / G. Valentini, G. Armano, M. Frasca, J. Lin, M. Mesiti, M. Re. - In: BIOINFORMATICS. - ISSN 1367-4803. - 32:18(2016 Sep), pp. 2872-2874. [10.1093/bioinformatics/btw235]

RANKS : a flexible tool for node label ranking and classification in biological networks

G. Valentini
Primo
;
M. Frasca;J. Lin;M. Mesiti
Penultimo
;
M. Re
Ultimo
2016-09

Abstract

RANKS is a flexible software package that can be easily applied to any bioinformatics task formalizable as ranking of nodes with respect to a property given as a label, such as automated protein function prediction, gene disease prioritization and drug repositioning. To this end RANKS provides an efficient and easy-to-use implementation of kernelized score functions, a semi-supervised algorithmic scheme embedding both local and global learning strategies for the analysis of biomolecular networks. To facilitate comparative assessment, baseline network-based methods, e.g. label propagation and random walk algorithms, have also been implemented.
associations; package; genes
Settore INF/01 - Informatica
Settore ING-INF/05 - Sistemi di Elaborazione delle Informazioni
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/422141
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