Fluorinated materials can be produced in order to combine an amorphous, homogenous structure and a refractive index very close to that of water. When in contact with aqueous solutions, such materials become barely visible. In these conditions, the adhesion of small amounts of molecules on their surface induces an optical signal that can be easily detected. This principle was exploited to realize novel label-free optical biosensors using either a dispersion of nanoparticles or a prism of fluorinated polymers as sensing substrates. The detection of specific molecular compounds in solution was achieved by suitable functionalization of the surface of the fluorinated materials.

Invisible fluorinated materials for optical sensing / R. Lanfranco, M. Buscaglia - In: Reference Module in Materials Science and Materials Engineering[s.l] : Elsevier, 2016. - ISBN 9780128035818. - pp. 1-10 [10.1016/B978-0-12-803581-8.04038-8]

Invisible fluorinated materials for optical sensing

R. Lanfranco;M. Buscaglia
2016

Abstract

Fluorinated materials can be produced in order to combine an amorphous, homogenous structure and a refractive index very close to that of water. When in contact with aqueous solutions, such materials become barely visible. In these conditions, the adhesion of small amounts of molecules on their surface induces an optical signal that can be easily detected. This principle was exploited to realize novel label-free optical biosensors using either a dispersion of nanoparticles or a prism of fluorinated polymers as sensing substrates. The detection of specific molecular compounds in solution was achieved by suitable functionalization of the surface of the fluorinated materials.
Dispersed phantom scatterer; Fluorinated polymers; Hepatitis B; Human immunodeficiency virus; Immunoassay; Label-free biosensor; Nanoparticles; Optical sensor; Reflective phantom interface; Surface functionalization
Settore FIS/07 - Fisica Applicata(Beni Culturali, Ambientali, Biol.e Medicin)
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/421563
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