Esophagectomy is a major surgical procedure. Due to the related morbidity and mortality, this operation should be carried out in high-volume referral centers by expert surgeons. Only patients in whom a complete resection is predictable at preoperative staging can consistently benefit from the operation. Chemoradiation therapy should be the first-line approach in patients with locally advanced tumors. A pathological complete response to neoadjuvant therapy is associated with a significantly improved long-term survival.
Surgery for esophageal carcinoma and the role of neoadjuvant therapy / L. Bonavina, D. Bona, A. Luporini, N. Navoni, R. Zucali. - In: ACTA BIO-MEDICA DE L'ATENEO PARMENSE. - ISSN 0392-4203. - 74:suppl. 2(2003), pp. 15-20.
Surgery for esophageal carcinoma and the role of neoadjuvant therapy
L. BonavinaPrimo
;D. BonaSecondo
;
2003
Abstract
Esophagectomy is a major surgical procedure. Due to the related morbidity and mortality, this operation should be carried out in high-volume referral centers by expert surgeons. Only patients in whom a complete resection is predictable at preoperative staging can consistently benefit from the operation. Chemoradiation therapy should be the first-line approach in patients with locally advanced tumors. A pathological complete response to neoadjuvant therapy is associated with a significantly improved long-term survival.Pubblicazioni consigliate
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