A major challenge in drug discovery is the definition of the activity of therapeutic compounds before they enter clinical trials. Currently, many tools are available to profile drug response at a multiparametric level. Furthermore, the novel discipline of systems biology is offering interpretative cues to the amount of data generated by the so-called omics technologies. Nonetheless, novel approaches are needed to comprehensively evaluate drug response. This review will describe a recent technology for protein profiling, the ImmunoCell-Array, which, in to the authors' opinion, can enter the scenario of profiling technologies with the goal of offering a comprehensive description of proteome dynamics in a cellular context.
ImmunoCell-Array : a novel technology for pathways discovery and cell profiling / L. Giorgetti, A. Zanardi, S. Venturini, R. Carbone. - In: EXPERT REVIEW OF PROTEOMICS. - ISSN 1478-9450. - 4:5(2007), pp. 609-616.
|Titolo:||ImmunoCell-Array : a novel technology for pathways discovery and cell profiling|
|Settore Scientifico Disciplinare:||Settore FIS/03 - Fisica della Materia|
|Data di pubblicazione:||2007|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1586/14789418.104.22.1689|
|Appare nelle tipologie:||01 - Articolo su periodico|