Human parvovirus 4 (PARV4) is a recently discovered member of the Parvoviridae. We investigated the presence of this virus in bone-marrow aspirates of 35 Italian patients with AIDS. Viral DNA was detected by polymerase chain reaction in over 40% of patients (16/35). The infection was most prevalent in injection drug users (IDU; 12/18; 66.7%) as opposed to non-IDU (4/17; 23.5%). PARV4 infection is widespread in Italian patients with AIDS.
Human parvovirus 4 in the bone marrow of Italian patients with AIDS / E. Longhi, G. Bestetti, V. Acquaviva, A. Foschi, R. Piolini, L. Meroni, C. Magni, S. Antinori, C. Parravicini, M. Corbellino. - In: AIDS. - ISSN 0269-9370. - 21:11(2007 Jul), pp. 1481-1483.
Human parvovirus 4 in the bone marrow of Italian patients with AIDS
E. Longhi;G. Bestetti;V. Acquaviva;A. Foschi;R. Piolini;S. Antinori;
2007
Abstract
Human parvovirus 4 (PARV4) is a recently discovered member of the Parvoviridae. We investigated the presence of this virus in bone-marrow aspirates of 35 Italian patients with AIDS. Viral DNA was detected by polymerase chain reaction in over 40% of patients (16/35). The infection was most prevalent in injection drug users (IDU; 12/18; 66.7%) as opposed to non-IDU (4/17; 23.5%). PARV4 infection is widespread in Italian patients with AIDS.
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