The bovine oxidized LDL receptor 1 (OLR1) was chosen as a candidate gene for association tests with milk composition traits. Genotyping of 773 Italian Brown Swiss for a SNP at position 8232 in OLR1 (NW_215807:g.8232C>A) revealed a frequency of 0.95 for the g.8232C allele. The University of Wisconsin Holstein resource population was genotyped for the OLR1 NW_215807:g.[7160C>T; 7161A>G; 8232C>A] SNPs, and four haplotypes were inferred based on the genotypes of sires and their daughters. Oxidized LDL receptor 1 haplotypes were significantly associated with fat percentage (P = 0.0015). Haplotype [C; A; C] was associated with a significant increase in fat percentage when compared with the other haplotypes.
|Titolo:||Additional support for an association between OLR1 and milk fat traits in cattle|
BAGNATO, ALESSANDRO (Ultimo)
|Parole Chiave:||Candidate gene; Cattle; Single nucleotide polymorphism|
|Settore Scientifico Disciplinare:||Settore AGR/17 - Zootecnica Generale e Miglioramento Genetico|
|Data di pubblicazione:||2007|
|Digital Object Identifier (DOI):||10.1111/j.1365-2052.2007.01584.x|
|Appare nelle tipologie:||01 - Articolo su periodico|