The bovine oxidized LDL receptor 1 (OLR1) was chosen as a candidate gene for association tests with milk composition traits. Genotyping of 773 Italian Brown Swiss for a SNP at position 8232 in OLR1 (NW_215807:g.8232C>A) revealed a frequency of 0.95 for the g.8232C allele. The University of Wisconsin Holstein resource population was genotyped for the OLR1 NW_215807:g.[7160C>T; 7161A>G; 8232C>A] SNPs, and four haplotypes were inferred based on the genotypes of sires and their daughters. Oxidized LDL receptor 1 haplotypes were significantly associated with fat percentage (P = 0.0015). Haplotype [C; A; C] was associated with a significant increase in fat percentage when compared with the other haplotypes.
Additional support for an association between OLR1 and milk fat traits in cattle / H. Khatib, G.J.M. Rosa, K. Weigel, F. Schiavini, E. Santus, A. Bagnato. - In: ANIMAL GENETICS. - ISSN 0268-9146. - 38:3(2007), pp. 308-310.
Titolo: | Additional support for an association between OLR1 and milk fat traits in cattle |
Autori: | BAGNATO, ALESSANDRO (Ultimo) |
Parole Chiave: | Candidate gene; Cattle; Single nucleotide polymorphism |
Settore Scientifico Disciplinare: | Settore AGR/17 - Zootecnica Generale e Miglioramento Genetico |
Data di pubblicazione: | 2007 |
Rivista: | |
Tipologia: | Article (author) |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1111/j.1365-2052.2007.01584.x |
Appare nelle tipologie: | 01 - Articolo su periodico |