PhoNeS (Photo Neutron Source) is an INFN project devoted to the optimization of the neutron production and moderation in radiotherapy linear accelerators. LinAcs producing high energy (15–25 MeV) photon beams are becoming widespread. At this energy neutron photo-production is unavoidable and the neutron dose must be controlled and reduced during normal radiotherapy. A technique known as BNCT (Boron Neutron Capture Therapy) uses neutrons for radiotherapic treatments:the cells are given a drug containing 10B which undergoes fission after neutron capture, inducing heavy damages to the DNA of the cell itself. This paper will describe the moderator developed by PhoNeS and the results in terms of neutron flux and spectrum and photon contamination of the measurements performed on several radiotherapy accelerators.
PhoNeS : a novel approach to BNCT with conventional radiotherapy accelerators / R. Bevilacqua, G. Giannini, F. Calligaris, D. Fontanarosa, F. Longo, G. Scian, P. Totaro, K. Vittor , E. Vallazza, M. Severgnini, R. Vidimari, G. Bartesaghi, V. Conti, V. Mascagna, C. Perboni, M. Prest, G. Gambarini, S. Gay, M.A. Valente, A. Mozzanica, A. Monti, A. Ostinelli, L. Azario, A. Fidanzio, A. Piermattei, O. Borla, E. Durisi, F. Fasolo, U. Nastasi, E. Perosino, A. Zanini, L. Tommasino. - In: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION A, ACCELERATORS, SPECTROMETERS, DETECTORS AND ASSOCIATED EQUIPMENT. - ISSN 0168-9002. - 572:1(2007), pp. 231-232.
PhoNeS : a novel approach to BNCT with conventional radiotherapy accelerators
G. Bartesaghi;V. Conti;G. Gambarini;S. Gay;M.A. Valente;
2007
Abstract
PhoNeS (Photo Neutron Source) is an INFN project devoted to the optimization of the neutron production and moderation in radiotherapy linear accelerators. LinAcs producing high energy (15–25 MeV) photon beams are becoming widespread. At this energy neutron photo-production is unavoidable and the neutron dose must be controlled and reduced during normal radiotherapy. A technique known as BNCT (Boron Neutron Capture Therapy) uses neutrons for radiotherapic treatments:the cells are given a drug containing 10B which undergoes fission after neutron capture, inducing heavy damages to the DNA of the cell itself. This paper will describe the moderator developed by PhoNeS and the results in terms of neutron flux and spectrum and photon contamination of the measurements performed on several radiotherapy accelerators.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
