KAT1 is a cloned plant potassium channel belonging to the superfamily of Shaker-like Kv channels. Previous studies have shown that 14-3-3 proteins significantly increase KAT1 current by modifying the channel open probability. Employing a 14-3-3 scavenger construct to lower the long-term availability of endogenous 14-3-3 proteins, we found that 14-3-3 proteins not only control the voltage dependency of the channel but also the number of channels in the plasma membrane.
14-3-3 proteins regulate the potassium channel KAT1 by dual modes / B. Sottocornola, S. Gazzarrini, C. Olivari, G. Romani, P. Valbuzzi, G. Thiel, A. Moroni. - In: PLANT BIOLOGY. - ISSN 1435-8603. - 10:2(2008), pp. 231-236.
14-3-3 proteins regulate the potassium channel KAT1 by dual modes
S. GazzarriniSecondo
;C. Olivari;A. MoroniUltimo
2008
Abstract
KAT1 is a cloned plant potassium channel belonging to the superfamily of Shaker-like Kv channels. Previous studies have shown that 14-3-3 proteins significantly increase KAT1 current by modifying the channel open probability. Employing a 14-3-3 scavenger construct to lower the long-term availability of endogenous 14-3-3 proteins, we found that 14-3-3 proteins not only control the voltage dependency of the channel but also the number of channels in the plasma membrane.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
