KAT1 is a cloned plant potassium channel belonging to the superfamily of Shaker-like Kv channels. Previous studies have shown that 14-3-3 proteins significantly increase KAT1 current by modifying the channel open probability. Employing a 14-3-3 scavenger construct to lower the long-term availability of endogenous 14-3-3 proteins, we found that 14-3-3 proteins not only control the voltage dependency of the channel but also the number of channels in the plasma membrane.
14-3-3 proteins regulate the potassium channel KAT1 by dual modes / B. Sottocornola, S. Gazzarrini, C. Olivari, G. Romani, P. Valbuzzi, G. Thiel, A. Moroni. - In: PLANT BIOLOGY. - ISSN 1435-8603. - 10:2(2008), pp. 231-236.
Titolo: | 14-3-3 proteins regulate the potassium channel KAT1 by dual modes |
Autori: | GAZZARRINI, SABRINA (Secondo) MORONI, ANNA (Ultimo) |
Parole Chiave: | 14-3-3 proteins ; gating K+ channel ; KAT1 ; modulation ; trafficking ; voltage-dependence |
Settore Scientifico Disciplinare: | Settore BIO/04 - Fisiologia Vegetale |
Data di pubblicazione: | 2008 |
Rivista: | |
Tipologia: | Article (author) |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1111/j.1438-8677.2007.00028.x |
Appare nelle tipologie: | 01 - Articolo su periodico |